It’s time for some memes about Marvel’s most beloved best frenemies, Spider-Man and Deadpool. Marvel has a lot of great team-ups in their vast catalog of characters, but none of them are quite as fun as these wisecracking BFFs.

They’ve had quite the relationship over the years. They can be anywhere from reluctant allies, to bitter rivals, to willing and witty partners in heroics. They might even be more than just friends, if you ask Deadpool. The two have crossed paths plenty of times in Marvel comic history, and even got their own series, Spider-Man/Deadpool, back in 2016. The series is ongoing, and the duo’s fanbase only seems to grow larger. Maybe someday we’ll see them together in ...

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